【佳學(xué)基因檢測(cè)】長(zhǎng)鏈非編碼 RNA FTX 在癌癥進(jìn)展中的生物學(xué)作用

品牌基因檢測(cè)中心引言

研究體會(huì)到《Biomed Pharmacother》在.?2022 Sep;153:113446.發(fā)表了一篇題目為《長(zhǎng)鏈非編碼 RNA FTX 在癌癥進(jìn)展中的生物學(xué)作用》腫瘤靶向藥物治療基因檢測(cè)臨床研究文章。該研究由Jinlan Yang,?Tianyin Qu,?Yajun Li,?Jingjing Ma,?Huangfei Yu?等完成。促進(jìn)了腫瘤的正確治療與個(gè)性化用藥的發(fā)展，進(jìn)一步強(qiáng)調(diào)了基因信息檢測(cè)與分析的重要性。

腫瘤靶向藥物及正確治療臨床研究?jī)?nèi)容關(guān)鍵詞：

代謝異常,癌癥, LncRNA FTX,轉(zhuǎn)移,移民,增殖

腫瘤靶向治療基因檢測(cè)臨床應(yīng)用結(jié)果

長(zhǎng)鏈非編碼 RNA (LncRNA) 涉及多種類型的癌癥，并積極參與腫瘤發(fā)生和疾病進(jìn)展。 LncRNA FTX 是位于 X 失活中心 (Xic) 的 FTX 基因的轉(zhuǎn)錄產(chǎn)物。 LncRNA FTX 已被證明可調(diào)節(jié)癌細(xì)胞增殖、遷移和異常代謝，并增加體內(nèi)腫瘤生長(zhǎng)和轉(zhuǎn)移。在此，我們總結(jié)了目前關(guān)于LncRNA FTX與惡性腫瘤相關(guān)分子和信號(hào)通路相互作用的研究，以更好地了解LncRNA FTX在癌癥進(jìn)展中的生物學(xué)作用。癌癥; LncRNA FTX；轉(zhuǎn)移;移民;增殖。

腫瘤發(fā)生與反復(fù)轉(zhuǎn)移國(guó)際數(shù)據(jù)庫(kù)描述：

Long non-coding RNAs (LncRNAs) are involved in several types of cancer and participate actively in tumorigenesis and disease progression. LncRNA FTX is the transcription product of the FTX gene located at the X-inactivation center (Xic). LncRNA FTX has been shown to regulate cancer cell proliferation, migration, and aberrant metabolism, as well as increase tumor growth and metastasis in vivo. Herein, we summarized currently available research on the interaction between LncRNA FTX and associated molecules and signaling pathways in malignant tumors to better understand the biological roles of LncRNA FTX in cancer progression.Keywords:?Aberrant metabolism; Cancer; LncRNA FTX; Metastasis; Migration; Proliferation.