【佳學基因檢測】1型神經(jīng)纖維瘤病成人的社會功能

品牌基因檢測怎么樣排隊

分析腫瘤基因檢測位點的全面性與正確性, 明白《Res Dev Disabil》在. 2013 Oct;34(10):3393-9.發(fā)表了一篇題目為《1型神經(jīng)纖維瘤病成人的社會功能》腫瘤靶向藥物治療基因檢測臨床研究文章。該研究由Natalie A Pride, Hilda Crawford, Jonathan M Payne, Kathryn N North等完成。促進了1型神經(jīng)纖維瘤病的正確治療與個性化用藥的發(fā)展，進一步強調(diào)了基因信息檢測與分析1型神經(jīng)纖維瘤病的重要性。

腫瘤靶向藥物及正確治療臨床研究內(nèi)容關(guān)鍵詞：

認知缺陷, 1型神經(jīng)纖維瘤病,社會認知,社交技能

腫瘤靶向治療基因檢測臨床應用結(jié)果

1型神經(jīng)纖維瘤病 (NF1) 是一種常見的單基因疾病，其特征在于多種皮膚、神經(jīng)和腫瘤表現(xiàn)。眾所周知，患有 NF1 的兒童與同伴互動較差，并且面臨社交技能缺陷的風險。然而，很少有研究檢查 NF1 成人的社會功能?；蚪獯a基因檢測旨在確定患有 NF1 的成年人是否有更大的社交技能受損風險，并確定社交技能缺陷的潛在風險因素?；蚪獯a基因檢測使用自我報告和觀察者報告的社會行為測量評估了 62 名 NF1 成人和 39 名對照者的社交技能?；蚪獯a基因檢測證明，與對照組相比，患有 NF1 的成年人表現(xiàn)出的親社會行為顯著減少。這種缺陷與社會處理能力有關(guān)，在男性中更為明顯。兩組之間反社會行為的頻率相當，但與 NF1 組的行為調(diào)節(jié)顯著相關(guān)。這些研究基因解碼基因檢測的研究結(jié)果表明，NF1 個體的社交技能差是由于親社會行為的缺陷，而不是反社會行為的增加。這將有助于設計旨在提高 NF1 患者社交技能的干預措施。關(guān)鍵詞：認知缺陷； 1型神經(jīng)纖維瘤??；社會認知;社交技能。

腫瘤發(fā)生與反復轉(zhuǎn)移國際數(shù)據(jù)庫描述：

Neurofibromatosis type 1 (NF1) is a common single-gene disorder characterised by a diverse range of cutaneous, neurological and neoplastic manifestations. It is well recognised that children with NF1 have poor peer interactions and are at risk for deficits in social skills. Few studies, however, have examined social functioning in adults with NF1. We aimed to determine whether adults with NF1 are at greater risk for impairment in social skills and to identify potential risk factors for social skills deficits. We evaluated social skills in 62 adults with NF1 and 39 controls using self-report and observer-report measures of social behaviour. We demonstrate that adults with NF1 exhibit significantly less prosocial behaviour than controls. This deficit was associated with social processing abilities and was more evident in males. The frequency of antisocial behaviour was comparable between the two groups, however was significantly associated with behavioural regulation in the NF1 group. These findings suggest that poor social skills in individuals with NF1 are due to deficits in prosocial behaviour, rather than an increase in antisocial behaviour. This will aid the design of interventions aimed at improving social skills in individuals with NF1.Keywords: Cognitive deficits; Neurofibromatosis type 1; Social cognition; Social skills.